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Symbol
Name
ID

Sgpl1
sphingosine phosphate lyase 1
MGI:1261415

Phenotype annotations related to renal/urinary system

Darker colors indicate more annotations

Human Phenotypes	Proteinuria	Podocyte foot process effacement	Mesangial hypercellularity	Diffuse mesangial sclerosis	Focal segmental glomerulosclerosis	Nephrotic syndrome	Steroid-resistant nephrotic syndrome	Stage 5 chronic kidney disease
Disease(s) Associated with SGPL1
nephrotic syndrome type 14

Mouse Phenotypes		kidney inflammation	abnormal kidney morphology	podocyte foot process effacement	absent podocyte slit diaphragm	abnormal renal glomerulus morphology	small kidney	pale kidney	abnormal urothelium morphology	abnormal kidney physiology
Availability	Mouse Genotype	kidney inflammation	abnormal kidney morphology	podocyte foot process effacement	absent podocyte slit diaphragm	abnormal renal glomerulus morphology	small kidney	pale kidney	abnormal urothelium morphology	abnormal kidney physiology
	Sgpl1^{Gt(OST58278)Lex}/Sgpl1^{Gt(OST58278)Lex}
	Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23